Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20987232 | 1.00 | HTT (0.46) | HTTDNM1ZDHHC20ZDHHC2HSP90AA1 | |
| Hydrochloric Acid SCHEMBL7100992 | 1.00 | HTT (0.46) | HTTDNM1ZDHHC20ZDHHC2HSP90AA1 | |
| Hydrochloric Acid SCHEMBL20987234 | 1.00 | HTT (0.46) | HTTDNM1ZDHHC20ZDHHC2HSP90AA1 | |
| SCHEMBL4423048 | 0.84 | ZDHHC20 (0.56) | DNM1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL4083031 | 0.84 | ZDHHC20 (0.56) | DNM1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL2874278 | 0.84 | ZDHHC20 (0.56) | DNM1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL12200640 | 0.84 | ZDHHC20 (0.56) | DNM1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL6515558 | 0.84 | ZDHHC20 (0.56) | DNM1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL7632696 | 0.84 | ZDHHC20 (0.56) | DNM1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL12200641 | 0.84 | ZDHHC20 (0.56) | DNM1ZDHHC20ZDHHC2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190153300-A1 | METHOD FOR PREPARING AN AQUEOUS POLYACRYLAMIDE SOLUTION | BASF SE (DE) | 2019-05-23 | — | — | US | disclosed |