Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.77 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | F3 | P13726 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | USP7 | Q93009 | 1/20 | 0.66 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.66 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.65 |
| ▸ | PYGM | P11217 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terminolic Acid SCHEMBL5796274 | 1.00 | PTPN1 (0.77) | PTPN1ALOX5USP2CYP3A4TDP1 | |
| Terminolic Acid SCHEMBL5796424 | 1.00 | PTPN1 (0.77) | PTPN1ALOX5USP2CYP3A4TDP1 | |
| Terminolic Acid SCHEMBL5798233 | 1.00 | PTPN1 (0.77) | PTPN1ALOX5USP2CYP3A4TDP1 | |
| Terminolic Acid SCHEMBL1048239 | 1.00 | PTPN1 (0.77) | PTPN1ALOX5USP2CYP3A4TDP1 | |
| Terminolic Acid SCHEMBL5796268 | 1.00 | PTPN1 (0.77) | PTPN1ALOX5USP2CYP3A4TDP1 | |
| Terminolic Acid SCHEMBL27133066 | 1.00 | PTPN1 (0.77) | PTPN1ALOX5USP2CYP3A4TDP1 | |
| Terminolic Acid SCHEMBL26940223 | 1.00 | PTPN1 (0.77) | PTPN1ALOX5USP2CYP3A4TDP1 | |
| SCHEMBL26940214 | 0.88 | PTPN1 (0.63) | PTPN1ALOX5USP2CYP3A4TDP1 | |
| Arjunolic Acid SCHEMBL24135094 | 0.87 | PTPN1 (1.00) | PTPN1ALOX5USP2CYP3A4TP53 | |
| Arjunolic Acid SCHEMBL18420183 | 0.87 | PTPN1 (1.00) | PTPN1ALOX5USP2CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742312-A | Sterilant compositions, kits and methods of use thereof | 柯姆尼治疗公司 | 2024-10-01 | — | — | CN | disclosed |
| EP-4153128-A1 | COMPOSITION COMBINING JONZAC THERMAL SPRING WATER AND A CENTELLA ASIATICA EXTRACT AND THE REPAIRING/HEALING EFFECT THEREOF | Laboratoires Léa (FR) | 2023-03-29 | — | — | EP | disclosed |
| WO-2023036404-A1 | TASTE BALANCING BOTANICAL COMPOUNDS | SYMRISE AG (DE) | 2023-03-16 | — | — | WO | disclosed |
| US-20170173059-A1 | Novel Combination of Naturally Occurring Compounds to Assist With Suspected Mycobacterial Infections Related to Autoimmune Conditions | MAGRONE JR NICHOLAS (US) | 2017-06-22 | — | — | US | disclosed |
| US-9487552-B2 | Method for preparing an extract of centella asiatica | Naturex, S.A. (FR) | 2016-11-08 | — | — | US | disclosed |
| US-8486900-B2 | Method for preparing a Centella asiatica extract rich in madecassoside and in terminoloside | BAYER CONSUMER CARE AG (CH) | 2013-07-16 | — | — | US | disclosed |
| US-20130172541-A1 | METHOD FOR PREPARING AN EXTRACT OF CENTELLA ASIATICA | Naturex, S.A. (FR) | 2013-07-04 | — | — | US | disclosed |
| US-20120178706-A1 | METHOD FOR PREPARING A CENTELLA ASIATICA EXTRACT RICH IN MADECASSOSIDE AND IN TERMINOLOSIDE | BAYER CONSUMER CARE AG (CH) | 2012-07-12 | — | — | US | disclosed |
| US-8163706-B2 | plant extracts is produced from solvent extraction, contains a triglucose-picene structure compounds; as antiinflammatory agents treating autoimmune disease, cosmetic composition for prevent aging and other skin disorders | BAYER CONSUMER CARE AG (CH) | 2012-04-24 | — | — | US | disclosed |
| US-7402669-B2 | plant extracts is produced from solvent extraction, contains a triglucose-picene structure compounds; as antiinflammatory agents treating autoimmune disease, cosmetic composition for prevent aging, and other skin disorders | BAYER CONSUMER CARE AG (CH) | 2008-07-22 | — | — | US | disclosed |
| US-20080118581-A1 | Method for preparing a centella asiatica extract rich in madecassoside and in terminoloside | BAYER CONSUMER CARE AG (CH) | 2008-05-22 | — | — | US | disclosed |
| CN-101076514-A | Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors | ABIOGEN PHARMA SPA (IT) | 2007-11-21 | — | — | CN | disclosed |
| US-20060235078-A1 | Insulin secretion potentiator | USE-TECHNO CORPORATION | 2006-10-19 | — | — | US | disclosed |
| EP-1674089-A1 | ACCELERATOR FOR INITIAL INSULIN SECRETION | Use-Techno Corporation (JP) | 2006-06-28 | — | — | EP | disclosed |
| WO-2006064583-A1 | TERPENE, METHOD FOR DETERMINING ITS BLOOD CONCENTRATION, AND METHOD FOR ANALYZING ITS PHARMACOKINETICS | USE-TECHNO CORPORATION (JP) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006054370-A1 | GLUCONEOGENESIS INHIBITING AGENT | USE-TECHNO CORPORATION (JP) | 2006-05-26 | — | — | WO | disclosed |
| US-20060106206-A1 | plant extracts is produced from solvent extraction, contains a triglucose-picene structure compounds; as antiinflammatory agents treating autoimmune disease, cosmetic composition for prevent aging, and other skin disorders | BAYER CONSUMER CARE AG | 2006-05-18 | — | — | US | disclosed |
| CN-1774257-A | Method for preparing a centella asiatica extracts rich in madecassoside and in terminoloside | BAYER CONSUMER CARE AG (CH) | 2006-05-17 | — | — | CN | disclosed |
| US-20050143464-A1 | With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts | USE-TECHNO CORPORATION | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143464-A1 | With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts | GPR119, IRS1, AMY1A | PTPN1 1873/4885ALOX5 511/4885USP2 3824/4885 |
| US-20120178706-A1 | METHOD FOR PREPARING A CENTELLA ASIATICA EXTRACT RICH IN MADECASSOSIDE AND IN TERMINOLOSIDE | CYP51A1, CYP46A1, GYPA | PTPN1 1677/4885ALOX5 70/4885USP2 599/4885 |
| US-20060106206-A1 | plant extracts is produced from solvent extraction, contains a triglucose-picene structure compounds; as antiinflammatory agents treating autoimmune disease, cosmetic composition for prevent aging, and other skin disorders | NFATC1, TNF, GLA | PTPN1 989/4885ALOX5 30/4885USP2 1156/4885 |
| US-20060235078-A1 | Insulin secretion potentiator | IAPP, GPR119, IRS1 | PTPN1 1481/4885ALOX5 3951/4885USP2 1979/4885 |
| US-20130172541-A1 | METHOD FOR PREPARING AN EXTRACT OF CENTELLA ASIATICA | CROCC, GYPA, GANC | PTPN1 2240/4885ALOX5 908/4885USP2 1711/4885 |
| US-20080118581-A1 | Method for preparing a centella asiatica extract rich in madecassoside and in terminoloside | CYP51A1, CYP46A1, GYPA | PTPN1 1677/4885ALOX5 70/4885USP2 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.