Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20218870 | 1.00 | CYP4F2 (0.32) | CYP4F2CYP4A11MAPK1MEN1KMT2A | |
| SCHEMBL14715868 | 1.00 | CYP4F2 (0.32) | CYP4F2CYP4A11MAPK1MEN1KMT2A | |
| SCHEMBL14715869 | 1.00 | CYP4F2 (0.32) | CYP4F2CYP4A11MAPK1MEN1KMT2A | |
| SCHEMBL14716058 | 0.86 | CTRC (0.32) | — | |
| SCHEMBL14716061 | 0.86 | CTRC (0.32) | — | |
| SCHEMBL14716060 | 0.86 | CTRC (0.32) | — | |
| SCHEMBL14716104 | 0.84 | BCHE (0.31) | CYP4F2CYP4A11MEN1KMT2ABCHE | |
| SCHEMBL14716101 | 0.84 | BCHE (0.31) | CYP4F2CYP4A11MEN1KMT2ABCHE | |
| SCHEMBL14719739 | 0.84 | BCHE (0.31) | CYP4F2CYP4A11MEN1KMT2ABCHE | |
| SCHEMBL14716102 | 0.84 | BCHE (0.31) | CYP4F2CYP4A11MEN1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130317245-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF | CHIROGATE INTERNATIONAL INC. (TW) | 2013-11-28 | — | — | US | disclosed |
| US-8524939-B2 | Intermediates for the synthesis of benzindene prostaglandins and preparations thereof | CHIROGATE INTERNATIONAL INC. (TW) | 2013-09-03 | — | — | US | disclosed |
| US-20130053581-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF | CHIROGATE INTERNATIONAL INC. | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053581-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF | PTGIS, PTGES, PTGS1 | CYP4F2 264/4885CYP4A11 128/4885MAPK1 1739/4885 |
| US-20130317245-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF | PTGIS, PTGES, PTGS1 | CYP4F2 264/4885CYP4A11 128/4885MAPK1 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.