Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 6/20 | 0.73 |
| ▸ | CDK1 | P06493 | 5/20 | 0.68 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13828289 | 0.85 | YTHDC1 (1.00) | YTHDC1CDK1CDK2CCNE2CCNE1 | |
| SCHEMBL13708308 | 0.81 | CDK1 (0.49) | YTHDC1CDK1CDK2CCNE2CCNE1 | |
| SCHEMBL129921 | 0.81 | CDK1 (1.00) | YTHDC1CDK1 | |
| SCHEMBL15756901 | 0.81 | YTHDC1 (0.69) | YTHDC1CDK1CDK2CCNE2CCNE1 | |
| SCHEMBL16131580 | 0.80 | PDE4A (0.48) | YTHDC1CDK1CDK2CCNE1PDE4A | |
| SCHEMBL21348744 | 0.78 | YTHDC1 (0.66) | YTHDC1CDK1 | |
| SCHEMBL15756616 | 0.78 | YTHDC1 (0.66) | YTHDC1CDK1CDK2CCNE2CCNE1 | |
| SCHEMBL183230 | 0.77 | CDK1 (0.66) | YTHDC1CDK1CDK2CCNE2CCNE1 | |
| SCHEMBL183098 | 0.77 | YTHDC1 (0.64) | YTHDC1CDK1CDK2CCNE2CCNE1 | |
| SCHEMBL29426225 | 0.77 | CDK1 (0.68) | YTHDC1CDK1CDK2CCNE2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265626-B1 | NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE | LCB PHARMA INC (CA) | 2019-05-15 | — | — | EP | disclosed |