Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21008151 | 0.89 | HRH4 (0.45) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL16922590 | 0.86 | HRH4 (0.59) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL21007009 | 0.83 | ATM (0.42) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL21008247 | 0.83 | GPR3 (0.35) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL21007301 | 0.81 | KDM4E (0.40) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL21008218 | 0.79 | HTR2C (0.40) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL21007011 | 0.79 | LIMK1 (0.39) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL21006938 | 0.79 | HTR2C (0.39) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL21007765 | 0.79 | HTR2C (0.39) | HRH4HTR2CPIK3CALIMK1CDK5 | |
| SCHEMBL21007300 | 0.78 | LIMK1 (0.40) | HRH4HTR2CPIK3CALIMK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11349081-B2 | Azaindolocarbazole compounds | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2022-05-31 | — | — | US | disclosed |
| US-20190148646-A1 | AZAINDOLOCARBAZOLE COMPOUNDS | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2019-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190148646-A1 | AZAINDOLOCARBAZOLE COMPOUNDS | SLC25A21, OXA1L, OCIAD1 | HRH4 2321/4885HTR2C 2510/4885PIK3CA 3428/4885 |
| US-11349081-B2 | Azaindolocarbazole compounds | SLC25A21, OXA1L, OCIAD1 | HRH4 2321/4885HTR2C 2510/4885PIK3CA 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.