SCHEMBL21012425

SCHEMBL21012425

CN(C)C(=O)COC(=O)c1c(F)ccc2c1OB(O)[C@@H]1C[C@H]21

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CAT P04040 1/20 0.63
KMT2A Q03164 3/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 3/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
MEN1 O00255 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23655054 1.00 CAT (0.63) CATKMT2ARAB9ANPC1ALDH1A1
SCHEMBL23655232 1.00 CAT (0.63) CATKMT2ARAB9ANPC1ALDH1A1
SCHEMBL21012459 0.92 CAT (0.56) CATKMT2AMEN1
SCHEMBL23654597 0.92 CAT (0.56) CATKMT2AMEN1
SCHEMBL21219556 0.89 CAT (0.54) CAT
SCHEMBL22854348 0.88 CAT (0.70) CATRAB9AALDH1A1KDM4EGAA
SCHEMBL22854346 0.88 CAT (0.70) CATRAB9AALDH1A1KDM4EGAA
SCHEMBL22854351 0.88 CAT (0.70) CATRAB9AALDH1A1KDM4EGAA
SCHEMBL22854352 0.88 CAT (0.70) CATRAB9AALDH1A1KDM4EGAA
SCHEMBL23655031 0.83 CAT (0.65) CATL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509475-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2025-12-30 US disclosed
US-20250034175-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA, INC. 2025-01-30 US disclosed
US-11999759-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2024-06-04 US disclosed
US-20220056055-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA, INC. 2022-02-24 US disclosed
US-11180512-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2021-11-23 US disclosed
EP-3478693-B1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA INC (US) 2021-07-21 EP disclosed
US-20200181177-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF THE MEDICINES COMPANY (SAN DIEGO), LLC 2020-06-11 US disclosed
US-10570159-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2020-02-25 US disclosed
US-10570159-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2020-02-25 US disclosed
US-20190233443-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF REMPEX PHARMACEUTICALS, INC. 2019-08-01 US disclosed
US-20190233443-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF REMPEX PHARMACEUTICALS, INC. 2019-08-01 US disclosed
US-10294249-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2019-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220056055-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF BTD, BLK, BCL6B CAT 106/4885KMT2A 1998/4885RAB9A 967/4885
US-10294249-B2 Boronic acid derivatives and therapeutic uses thereof BTD, BLK, BCL6B CAT 106/4885KMT2A 1998/4885RAB9A 967/4885
US-20200181177-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF BTD, BLK, BCL6B CAT 106/4885KMT2A 1998/4885RAB9A 967/4885
US-10570159-B2 Boronic acid derivatives and therapeutic uses thereof BTD, BLK, BCL6B CAT 106/4885KMT2A 1998/4885RAB9A 967/4885
US-11180512-B2 Boronic acid derivatives and therapeutic uses thereof BTD, BLK, BCL6B CAT 106/4885KMT2A 1998/4885RAB9A 967/4885
US-12509475-B2 Boronic acid derivatives and therapeutic uses thereof LBR, BLVRB, SRR CAT 2800/4885KMT2A 3373/4885RAB9A 1419/4885
US-11999759-B2 Boronic acid derivatives and therapeutic uses thereof BTD, BLK, BCL6B CAT 106/4885KMT2A 1998/4885RAB9A 967/4885
US-20190233443-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF BTD, BLK, BCL6B CAT 106/4885KMT2A 1998/4885RAB9A 967/4885
US-20250034175-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF BTD, BLK, BCL6B CAT 106/4885KMT2A 1998/4885RAB9A 967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.