Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.53 |
| ▸ | ATP4A | P20648 | 1/20 | 0.47 |
| ▸ | ATP4B | P51164 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21017926 | 0.91 | ALDH1A1 (0.49) | ACHECHEK2ATP4AATP4BALDH1A1 | |
| SCHEMBL21017655 | 0.90 | ACHE (0.65) | ACHECHEK2ATP4AATP4BALOX5 | |
| SCHEMBL20982633 | 0.89 | CHEK2 (0.61) | ACHECHEK2ATP4AATP4BALOX5 | |
| SCHEMBL21017226 | 0.85 | ALDH1A1 (0.48) | ACHECHEK2ATP4AATP4BALDH1A1 | |
| SCHEMBL20982555 | 0.85 | ACHE (0.59) | ACHECHEK2ATP4AATP4BALOX5 | |
| SCHEMBL20982498 | 0.84 | CHEK2 (0.60) | ACHECHEK2ATP4AATP4BALOX5 | |
| SCHEMBL21017825 | 0.84 | ACHE (0.67) | ACHECHEK2ATP4AATP4BALOX5 | |
| SCHEMBL21017657 | 0.84 | ACHE (0.50) | ACHECHEK2ALDH1A1PDGFRAHRH4 | |
| SCHEMBL21017228 | 0.81 | ACHE (0.66) | ACHECHEK2ATP4AATP4BALOX5 | |
| SCHEMBL20982619 | 0.81 | CHEK2 (0.72) | ACHECHEK2ATP4AATP4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190152924-A1 | BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING THE SAME | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152924-A1 | BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING THE SAME | HNRNPH1, HNRNPH3, HNRNPUL2 | ACHE 2382/4885CHEK2 1163/4885ATP4A 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.