Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.66 |
| ▸ | CPB1 | P15086 | 1/20 | 0.63 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGAV | P06756 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20272626 | 0.96 | SIRT2 (0.60) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18907025 | 0.94 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157482 | 0.94 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157462 | 0.94 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL18907028 | 0.94 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14157463 | 0.94 | FOLH1 (0.72) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL21018995 | 0.93 | SIRT2 (0.62) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL8641871 | 0.92 | FOLH1 (0.69) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL14519208 | 0.92 | FOLH1 (0.69) | FOLH1CPB1CPB2SIRT2SIRT1 | |
| SCHEMBL12874103 | 0.91 | SIRT2 (0.65) | FOLH1CPB1CPB2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11173214-B2 | Antibody-drug conjugates comprising branched linkers and methods related thereto | LEGOCHEM BIOSCIENCES, INC. (KR) | 2021-11-16 | — | — | US | disclosed |
| US-11167040-B2 | Conjugates comprising peptide groups and methods related thereto | LEGOCHEM BIOSCIENCES, INC. (KR) | 2021-11-09 | — | — | US | disclosed |
| US-20200297865-A1 | CONJUGATES COMPRISING SELF-IMMOLATIVE GROUPS AND METHODS RELATED THERETO | LIGACHEM BIOSCIENCES INC. (KR) | 2020-09-24 | — | — | US | disclosed |
| US-20190151465-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING BRANCHED LINKERS AND METHODS RELATED THERETO | LIGACHEM BIOSCIENCES INC. (KR) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151465-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING BRANCHED LINKERS AND METHODS RELATED THERETO | PA2G4, FCGRT, CLTB | FOLH1 155/4885CPB1 1619/4885CPB2 1208/4885 |
| US-11167040-B2 | Conjugates comprising peptide groups and methods related thereto | DAO, LPO, TYRO3 | FOLH1 161/4885CPB1 1181/4885CPB2 849/4885 |
| US-11173214-B2 | Antibody-drug conjugates comprising branched linkers and methods related thereto | PA2G4, FCGRT, CLTB | FOLH1 155/4885CPB1 1619/4885CPB2 1208/4885 |
| US-20200297865-A1 | CONJUGATES COMPRISING SELF-IMMOLATIVE GROUPS AND METHODS RELATED THERETO | LPO, NOXO1, DAO | FOLH1 453/4885CPB1 1718/4885CPB2 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.