Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021288 | 0.83 | SMN1; SMN2 (0.43) | RORCMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL21022158 | 0.82 | RORC (0.47) | RORCMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL21021868 | 0.73 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL18148116 | 0.70 | RORC (1.00) | RORCMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL21021155 | 0.67 | GAA (0.61) | MAPTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL14328942 | 0.66 | POLB (0.50) | MAPTLMNAPOLBALDH1A1HPGD | |
| SCHEMBL18160281 | 0.65 | RORC (0.67) | RORCMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL27293846 | 0.65 | HPGD (0.61) | MAPTSMN1; SMN2POLBALDH1A1HPGD | |
| SCHEMBL21021569 | 0.65 | TAS1R3 (0.44) | MAPTSMN1; SMN2LMNAALDH1A1TAS1R3 | |
| SCHEMBL13433106 | 0.64 | NPC1 (0.61) | LMNAPOLBALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |