Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 11/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020730 | 0.79 | RAB9A (0.42) | KDM4ELMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21020549 | 0.76 | TDP1 (0.44) | LMNARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL21021193 | 0.73 | KMT2A (0.40) | RAB9ANPC1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL21021757 | 0.73 | MEN1 (0.54) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21019686 | 0.73 | RAB9A (0.42) | KDM4ELMNARAB9ANPC1MAPT | |
| SCHEMBL19651332 | 0.72 | KDM4E (0.70) | KDM4ELMNARAB9ANPC1MAPT | |
| SCHEMBL16883496 | 0.72 | KDM4E (0.62) | KDM4ELMNARAB9ANPC1MAPT | |
| SCHEMBL18160436 | 0.72 | RAB9A (0.67) | KDM4ELMNARAB9ANPC1MAPT | |
| SCHEMBL19121973 | 0.72 | RAB9A (0.63) | KDM4ELMNARAB9ANPC1MAPT | |
| SCHEMBL21022158 | 0.72 | RORC (0.47) | KDM4ELMNARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |