Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20934668 | 0.82 | ASGR1 (0.30) | — | |
| SCHEMBL24466689 | 0.77 | ASGR1 (0.33) | — | |
| SCHEMBL18347976 | 0.69 | EPHX1 (0.35) | — | |
| SCHEMBL25543880 | 0.68 | KMT2A (0.31) | KMT2ASMN1; SMN2 | |
| SCHEMBL31424427 | 0.68 | — | — | |
| SCHEMBL25854704 | 0.66 | EPHX2 (0.41) | KMT2ASMN1; SMN2 | |
| SCHEMBL13923562 | 0.66 | MME (0.36) | — | |
| SCHEMBL22585266 | 0.66 | EPHX1 (0.30) | — | |
| SCHEMBL15199506 | 0.66 | EPHX1 (0.34) | — | |
| SCHEMBL25545350 | 0.64 | GRM1 (0.36) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213107-A1 | TERTIARY ALCOHOLS AS PI3K-y INHIBITORS | INCYTE CORPORATION | 2022-07-07 | — | — | US | disclosed |
| US-11225486-B2 | Tertiary alcohols as PI3K-γ inhibitors | INCYTE CORPORATION (US) | 2022-01-18 | — | — | US | disclosed |
| US-20200385392-A1 | TERTIARY ALCOHOLS AS PI3K-y INHIBITORS | INCYTE CORPORATION | 2020-12-10 | — | — | US | disclosed |
| US-10738057-B2 | Tertiary alcohols as PI3K-γ inhibitors | INCYTE CORPORATION (US) | 2020-08-11 | — | — | US | disclosed |
| US-20190152975-A1 | TERTIARY ALCOHOLS AS PI3K-y INHIBITORS | INCYTE CORPORATION | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152975-A1 | TERTIARY ALCOHOLS AS PI3K-y INHIBITORS | PIK3R5, PIK3R1, PIK3CD | KMT2A 2694/4885SMN1; SMN2 1125/4885 |
| US-10738057-B2 | Tertiary alcohols as PI3K-γ inhibitors | PIK3R5, PIK3CG, PIK3CD | KMT2A 3252/4885SMN1; SMN2 1086/4885 |
| US-20220213107-A1 | TERTIARY ALCOHOLS AS PI3K-y INHIBITORS | PIK3R5, PIK3R1, PIK3CD | KMT2A 2694/4885SMN1; SMN2 1125/4885 |
| US-20200385392-A1 | TERTIARY ALCOHOLS AS PI3K-y INHIBITORS | PIK3R5, PIK3R1, PIK3CD | KMT2A 2694/4885SMN1; SMN2 1125/4885 |
| US-11225486-B2 | Tertiary alcohols as PI3K-γ inhibitors | PIK3R5, PIK3CG, PIK3CD | KMT2A 3252/4885SMN1; SMN2 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.