SCHEMBL20934668

SCHEMBL20934668

CC(=O)NC12COC(CO)(C1)C2

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ASGR1 P07306 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31424427 0.85 — —
SCHEMBL19748720 0.84 — —
SCHEMBL24466689 0.83 ASGR1 (0.33) ASGR1
SCHEMBL21023375 0.82 KMT2A (0.30) —
SCHEMBL16118629 0.70 KDM4E (0.37) —
SCHEMBL11224012 0.70 KDM4E (0.37) —
SCHEMBL31493439 0.69 ALDH1A1 (0.30) —
SCHEMBL29602607 0.68 — —
SCHEMBL25433101 0.67 — —
SCHEMBL18214755 0.67 EPHX1 (0.39) ASGR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431365-A Phenyl heterocyclic derivative-containing regulator and preparation method and application thereof 江苏豪森药业集团有限公司 2025-02-14 — — CN disclosed
EP-3697789-B1 CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED BY TERTIARY HYDROXY GROUPS AS PI3K-GAMMA INHIBITORS INCYTE CORP (US) 2021-09-29 — — EP disclosed
WO-2019079469-A1 CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED BY TERTIARY HYDROXY GROUPS AS PI3K-GAMMA INHIBITORS INCYTE CORPORATION (US) 2019-04-25 — — WO disclosed
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