Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954634 | 0.84 | CRBN (0.35) | CRBNIL1BPDE4BPDE3APLAT | |
| SCHEMBL21023766 | 0.79 | PLAT (0.38) | GAAPDE4BPDE3APLATNR3C2 | |
| SCHEMBL21780763 | 0.78 | GAA (0.40) | GAANR3C2TGFBR1LMNATP53 | |
| SCHEMBL21023577 | 0.78 | TGFBR1 (0.44) | GAAPLATTGFBR1 | |
| SCHEMBL18164107 | 0.75 | GAA (0.41) | GAANR3C2TGFBR1LMNATP53 | |
| SCHEMBL21024096 | 0.75 | GAA (0.44) | GAANR3C2TGFBR1LMNA | |
| SCHEMBL14638771 | 0.75 | PLAT (0.45) | GAAPLATNR3C2TGFBR1IRAK4 | |
| SCHEMBL12912163 | 0.74 | GAA (0.43) | GAANR3C2LMNACYP2C9CYP2C19 | |
| SCHEMBL18163942 | 0.72 | GAA (0.39) | GAANR3C2TGFBR1LMNATP53 | |
| SCHEMBL18164033 | 0.72 | GAA (0.36) | GAANR3C2TGFBR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080087-B1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORP (US) | 2019-05-22 | — | — | EP | disclosed |