Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19105611 | 0.87 | TGFBR1 (0.35) | MAP3K12TGFBR1TRPV1NR3C2MEN1 | |
| SCHEMBL19954553 | 0.81 | NR3C2 (0.40) | MAP3K12TGFBR1TRPV1NR3C2MEN1 | |
| SCHEMBL19954663 | 0.81 | NR3C2 (0.38) | MAP3K12TGFBR1TRPV1NR3C2MEN1 | |
| SCHEMBL19954538 | 0.81 | AR (0.40) | TRPV1NR3C2 | |
| SCHEMBL19954610 | 0.81 | PDE7A (0.39) | TRPV1NR3C2MEN1KMT2A | |
| SCHEMBL19954523 | 0.80 | TGFBR1 (0.35) | MAP3K12TGFBR1TRPV1NR3C2MEN1 | |
| SCHEMBL19954571 | 0.80 | NR3C2 (0.34) | MAP3K12TGFBR1TRPV1NR3C2 | |
| SCHEMBL21024127 | 0.80 | NR3C2 (0.40) | MAP3K12TGFBR1TRPV1NR3C2MEN1 | |
| SCHEMBL19954613 | 0.80 | MEN1 (0.38) | TGFBR1TRPV1NR3C2MEN1KMT2A | |
| SCHEMBL21023784 | 0.78 | NR3C2 (0.36) | MAP3K12TGFBR1TRPV1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080087-B1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORP (US) | 2019-05-22 | — | — | EP | disclosed |