SCHEMBL21024766

SCHEMBL21024766

CCCCC1(CCCC)c2cc(C(=O)C(C)(C)O)ccc2-c2ccc(N3CCOCC3)cc21

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 3/20 0.42
▸ MAPT P10636 6/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ GSK3B P49841 1/20 0.39
▸ LMNA P02545 3/20 0.38
▸ ALDH1A1 P00352 4/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ PRKDC P78527 2/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ CNR1 P21554 2/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ CNR2 P34972 1/20 0.36
▸ KMO O15229 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23805882 0.89 PDK2 (0.40) PDK2MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL23805884 0.81 PDK2 (0.39) PDK2MAPTSMN1; SMN2LMNAALDH1A1
SCHEMBL21024702 0.79 PDK2 (0.39) PDK2MAPTSMN1; SMN2GSK3BLMNA
SCHEMBL22474742 0.79 ALDH1A1 (0.44) PDK2SMN1; SMN2ALDH1A1MAPK1CNR2
SCHEMBL29987669 0.79 ALDH1A1 (0.44) PDK2SMN1; SMN2ALDH1A1MAPK1CNR2
SCHEMBL30569665 0.79 ALDH1A1 (0.44) PDK2SMN1; SMN2ALDH1A1MAPK1CNR2
SCHEMBL21025023 0.78 PDK2 (0.45) PDK2
SCHEMBL23805898 0.78 ALDH1A1 (0.43) MAPTSMN1; SMN2RAB9AALDH1A1MEN1
SCHEMBL23805883 0.77 ALDH1A1 (0.42) PDK2MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL21024767 0.77 ALDH1A1 (0.57) MAPTSMN1; SMN2NPC1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514135-B1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-04-21 — — EP disclosed
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
EP-3514135-A1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD Changzhou Tronly Advanced Electronic Materials Co., Ltd. (CN) 2019-07-24 — — EP disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S PDK2 3423/4885MAPT 3789/4885SMN1; SMN2 3266/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S PDK2 3423/4885MAPT 3789/4885SMN1; SMN2 3266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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