SCHEMBL21024702

SCHEMBL21024702

C=CCCC1(CCC=C)c2cc(C(=O)C(O)(CC)CC)ccc2-c2ccc(N3CCOCC3)cc21

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 3/20 0.39
▸ PTPN1 P18031 1/20 0.37
▸ MAPT P10636 5/20 0.36
▸ LMNA P02545 2/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ GSK3B P49841 1/20 0.36
▸ PRKDC P78527 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ SLC13A5 Q86YT5 1/20 0.33
▸ ESR1 P03372 1/20 0.33
▸ KMO O15229 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ PLOD2 O00469 1/20 0.33
▸ PLOD3 O60568 1/20 0.33
▸ PLOD1 Q02809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21024766 0.79 PDK2 (0.42) PDK2MAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL21183160 0.75 PDK2 (0.37) PDK2PTPN1
SCHEMBL23805882 0.75 PDK2 (0.40) PDK2MAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL23805884 0.71 PDK2 (0.39) PDK2MAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL21024699 0.70 ALDH1A1 (0.48) PDK2MAPTLMNASMN1; SMN2GSK3B
SCHEMBL23805872 0.70 ALDH1A1 (0.48) PDK2PTPN1SMN1; SMN2L3MBTL1MEN1
SCHEMBL23805894 0.68 PDK2 (0.44) PDK2MAPTLMNASMN1; SMN2L3MBTL1
SCHEMBL22745172 0.67 PDK2 (0.34) PDK2ALDH1A1
SCHEMBL23805867 0.67 PDK2 (0.42) PDK2MAPTSMN1; SMN2L3MBTL1PRKDC
SCHEMBL21024704 0.66 GSK3B (0.41) PDK2MAPTLMNASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S PDK2 3423/4885PTPN1 2182/4885MAPT 3789/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S PDK2 3423/4885PTPN1 2182/4885MAPT 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback