Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165510 | 0.88 | ALOX5 (0.55) | ALOX5MEN1KMT2ARAB9ACNR2 | |
| SCHEMBL21025254 | 0.85 | ALOX5 (0.55) | ALOX5ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL12434956 | 0.76 | MEN1 (0.48) | ALOX5UTS2RALDH1A1MEN1KMT2A | |
| SCHEMBL956546 | 0.73 | MEN1 (0.48) | ALOX5ALDH1A1MEN1KMT2ACNR2 | |
| SCHEMBL18627485 | 0.72 | ALOX5 (0.45) | ALOX5ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL9474906 | 0.71 | ALOX5 (0.91) | ALOX5 | |
| SCHEMBL23095298 | 0.70 | ALOX5 (0.43) | ALOX5MEN1KMT2ARAB9ACNR2 | |
| SCHEMBL17054176 | 0.68 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2A | |
| SCHEMBL956471 | 0.68 | ALOX5 (0.41) | ALOX5ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL956469 | 0.68 | ALOX5 (0.41) | ALOX5ALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119772-B1 | HETEROARYL SIK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2019-05-22 | — | — | EP | disclosed |