SCHEMBL21025504

SCHEMBL21025504

CCC1(CC)c2ccccc2-c2ccc(C(=O)c3ccccc3C)cc21

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.44
▸ HTT P42858 1/20 0.44
▸ MAPK13 O15264 2/20 0.41
▸ MAPK12 P53778 2/20 0.41
▸ MAPK11 Q15759 2/20 0.41
▸ MAPK14 Q16539 2/20 0.41
▸ PDK2 Q15119 12/20 0.41
▸ APEX1 P27695 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21025031 0.96 ALDH1A1 (0.47) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL17084351 0.90 ALDH1A1 (0.42) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL21024696 0.89 ALDH1A1 (0.41) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL21168758 0.88 PDK2 (0.41) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL21025038 0.86 ALDH1A1 (0.39) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL12928474 0.85 CDC25B (0.49) ALDH1A1PDK2APEX1
SCHEMBL132972 0.83 ALDH1A1 (0.48) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL21025032 0.82 ALDH1A1 (0.47) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL17084352 0.81 PDK2 (0.42) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL30266914 0.81 PDK2 (0.42) ALDH1A1HTTMAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514135-B1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-04-21 — — EP disclosed
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
EP-3514135-A1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD Changzhou Tronly Advanced Electronic Materials Co., Ltd. (CN) 2019-07-24 — — EP disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S ALDH1A1 1364/4885HTT 1777/4885MAPK13 3961/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S ALDH1A1 1364/4885HTT 1777/4885MAPK13 3961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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