SCHEMBL21025038

SCHEMBL21025038

CCOC(=O)C(=O)c1ccc2c(c1)C(CC)(CC)c1cc(C(=O)c3ccccc3C)ccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.39
▸ HTT P42858 2/20 0.39
▸ GAA P10253 3/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ ATM Q13315 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ MAPK13 O15264 3/20 0.37
▸ MAPK12 P53778 3/20 0.37
▸ MAPK11 Q15759 3/20 0.37
▸ MAPK14 Q16539 3/20 0.37
▸ LMNA P02545 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ PKM P14618 1/20 0.37
▸ PDK2 Q15119 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ DHODH Q02127 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21025031 0.89 ALDH1A1 (0.47) ALDH1A1HTTGAARAB9AMEN1
SCHEMBL21024696 0.87 ALDH1A1 (0.41) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL21025428 0.87 ALDH1A1 (0.45) ALDH1A1HTTMEN1KMT2AATM
SCHEMBL21025504 0.86 ALDH1A1 (0.44) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL21025427 0.84 RAB9A (0.41) ALDH1A1HTTGAARAB9AMEN1
SCHEMBL21024709 0.81 ALDH1A1 (0.41) ALDH1A1HTTRAB9AMEN1KMT2A
SCHEMBL17084351 0.76 ALDH1A1 (0.42) ALDH1A1HTTMAPK13MAPK12MAPK11
SCHEMBL30266914 0.75 PDK2 (0.42) ALDH1A1HTTRAB9AMEN1KMT2A
SCHEMBL17084352 0.75 PDK2 (0.42) ALDH1A1HTTRAB9AMEN1KMT2A
SCHEMBL21636281 0.75 KDM4E (0.49) ALDH1A1HTTMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514135-B1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-04-21 — — EP disclosed
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
EP-3514135-A1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD Changzhou Tronly Advanced Electronic Materials Co., Ltd. (CN) 2019-07-24 — — EP disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S ALDH1A1 1364/4885HTT 1777/4885GAA 4530/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S ALDH1A1 1364/4885HTT 1777/4885GAA 4530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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