Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.35 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ugandensolide SCHEMBL21025899 | 0.64 | MAPK1 (0.31) | MAPK1CYP3A4NFKB1ADCY1TSHR | |
| SCHEMBL30498603 | 0.61 | MAPT (0.41) | MAPK1CYP3A4NFKB1ADCY1TSHR | |
| SCHEMBL21585135 | 0.61 | MAPK1 (0.40) | MAPK1CYP3A4NFKB1ADCY1TSHR | |
| SCHEMBL24402207 | 0.60 | MAPK1 (0.35) | MAPK1CYP3A4NFKB1ADCY1TSHR | |
| SCHEMBL14982984 | 0.60 | CYP3A4 (0.37) | MAPK1CYP3A4NFKB1TSHRKMT2A | |
| SCHEMBL30200341 | 0.59 | PTPN2 (0.38) | MAPK1CYP3A4NFKB1ADCY1TSHR | |
| SCHEMBL7811925 | 0.58 | CYP3A4 (0.33) | MAPK1CYP3A4NFKB1KMT2APLA2G1B | |
| SCHEMBL4688150 | 0.57 | — | — | |
| SCHEMBL21026193 | 0.57 | MAPK1 (0.38) | MAPK1CYP3A4NFKB1ADCY1TSHR | |
| SCHEMBL9694551 | 0.57 | POLB (0.36) | CYP3A4KMT2ACYP2D6CHRM2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190150437-A1 | USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS | OHIO STATE INNOVATION FOUNDATION | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190150437-A1 | USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS | NOTUM, DDT, CYP51A1 | MAPK1 4776/4885CYP3A4 219/4885NFKB1 3371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.