Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146224 | 0.79 | CA2 (0.34) | CA2 | |
| SCHEMBL28093194 | 0.76 | CA2 (0.41) | CA2 | |
| SCHEMBL26842478 | 0.74 | KDM4E (0.36) | — | |
| SCHEMBL20146546 | 0.68 | ADORA2A (0.33) | CYP1A2CA2 | |
| SCHEMBL31441244 | 0.66 | NEK1 (0.32) | CA2 | |
| SCHEMBL26014312 | 0.66 | NEK1 (0.32) | CA2 | |
| SCHEMBL31441242 | 0.66 | ADORA2A (0.31) | CA2 | |
| SCHEMBL2607619 | 0.66 | CA2 (0.46) | CA2 | |
| SCHEMBL2607562 | 0.66 | CA2 (0.46) | CA2 | |
| SCHEMBL23328255 | 0.65 | CYP2A6 (0.31) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301277-B2 | Substituted ureas and methods of treating mental illness using the same | ZHEJIANG JINGXIN PHARMACEUTICAL CO., LTD. (CN) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301277-B2 | Substituted ureas and methods of treating mental illness using the same | CRHR1, UTS2R, HTR2C | CYP17A1 2268/4885CYP1A2 1607/4885CA2 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.