Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027688 | 0.83 | SIGMAR1 (0.35) | SIGMAR1ITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL17150483 | 0.83 | KDM4E (0.36) | SIGMAR1ALOX15KDM4EALDH1A1TDP1 | |
| SCHEMBL23336316 | 0.82 | SIGMAR1 (0.37) | SIGMAR1ITGB3ITGA2BALOX15KDM4E | |
| SCHEMBL19040084 | 0.81 | KDM4E (0.36) | SIGMAR1ALOX15KDM4EALDH1A1TDP1 | |
| SCHEMBL19054969 | 0.80 | SIGMAR1 (0.38) | SIGMAR1ALOX15KDM4EALDH1A1TDP1 | |
| SCHEMBL16665113 | 0.80 | SIGMAR1 (0.38) | SIGMAR1ALOX15KDM4EALDH1A1CHRM1 | |
| SCHEMBL29659499 | 0.79 | SMN1; SMN2 (0.35) | HRH3 | |
| SCHEMBL16653865 | 0.77 | L3MBTL1 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL29265688 | 0.77 | L3MBTL1 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16653961 | 0.77 | PAOX (0.38) | SIGMAR1ALOX15KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489232-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2019-05-29 | — | — | EP | disclosed |