Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351266 | 0.81 | — | — | |
| SCHEMBL17528672 | 0.81 | — | — | |
| SCHEMBL18822638 | 0.76 | ANPEP (0.44) | GSRTRPV1TRPA1 | |
| SCHEMBL15868808 | 0.76 | ANPEP (0.44) | GSRTRPV1TRPA1 | |
| SCHEMBL24817188 | 0.76 | ANPEP (0.44) | GSRTRPV1TRPA1 | |
| SCHEMBL16247205 | 0.74 | ANPEP (0.42) | GSRTRPV1TRPA1 | |
| SCHEMBL8160766 | 0.73 | — | — | |
| SCHEMBL9436941 | 0.73 | DNM1 (0.47) | GSR | |
| SCHEMBL22126177 | 0.71 | TRPV1 (0.38) | GSRTRPV1TRPA1 | |
| SCHEMBL23011848 | 0.71 | TRPV1 (0.38) | GSRTRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669241-B2 | PTEN binding compounds, formulations, and uses thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190161450-A1 | PTEN BINDING COMPOUNDS, FORMULATIONS, AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669241-B2 | PTEN binding compounds, formulations, and uses thereof | PTEN, EYA2, PIK3CA | GSR 4681/4885RNPEP 4052/4885TRPV1 4265/4885 |
| US-20190161450-A1 | PTEN BINDING COMPOUNDS, FORMULATIONS, AND USES THEREOF | PTEN, EYA2, PIK3CA | GSR 4681/4885RNPEP 4052/4885TRPV1 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.