Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028018 | 0.86 | PTGDR2 (0.34) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| SCHEMBL21027972 | 0.81 | PTGDR2 (0.45) | KMT2AMEN1L3MBTL1RAB9APTGDR2 | |
| SCHEMBL21027857 | 0.77 | PTGDR2 (0.47) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL21027976 | 0.77 | PTGDR2 (0.49) | ATMPTGDR2CYP3A4 | |
| SCHEMBL21028291 | 0.74 | PTGDR2 (0.42) | ALDH1A1PTGDR2 | |
| SCHEMBL21028085 | 0.71 | PTGDR2 (0.43) | PTGDR2CYP3A4 | |
| SCHEMBL21027858 | 0.71 | PTGDR2 (0.50) | PTGDR2 | |
| SCHEMBL21027975 | 0.70 | PTGDR2 (0.44) | KMT2AKDM4EMEN1GLACASP1 | |
| SCHEMBL21028077 | 0.68 | MEN1 (0.41) | ALDH1A1ATMKMT2AKDM4EMEN1 | |
| SCHEMBL21028014 | 0.67 | PTGDR2 (0.42) | KMT2AMEN1RAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |