Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028015 | 0.86 | ALDH1A1 (0.38) | PTGDR2NPC1RAB9ASMN1; SMN2TSPO | |
| SCHEMBL21028085 | 0.76 | PTGDR2 (0.43) | PTGDR2PTGDRCYP3A4CYP2C9 | |
| SCHEMBL21027976 | 0.75 | PTGDR2 (0.49) | PTGDR2PTGDRCYP3A4CYP2C9 | |
| SCHEMBL21027972 | 0.70 | PTGDR2 (0.45) | PTGDR2PTGDRRAB9AMEN1KMT2A | |
| SCHEMBL21028291 | 0.69 | PTGDR2 (0.42) | PTGDR2PTGDRTDP1 | |
| SCHEMBL21027858 | 0.67 | PTGDR2 (0.50) | PTGDR2PTGDR | |
| SCHEMBL21027857 | 0.67 | PTGDR2 (0.47) | PTGDR2PTGDRSMN1; SMN2LMNAMAPT | |
| SCHEMBL21027975 | 0.61 | PTGDR2 (0.44) | PTGDR2PTGDRMAPTCYP3A4MEN1 | |
| SCHEMBL21028077 | 0.58 | MEN1 (0.41) | TSPOMAPTCYP3A4CYP2C19MEN1 | |
| SCHEMBL21609586 | 0.56 | ALDH1A1 (0.44) | SMN1; SMN2LMNAMAPTHTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |