Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028003 | 0.82 | PTGDR2 (0.49) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028085 | 0.80 | PTGDR2 (0.43) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028015 | 0.74 | ALDH1A1 (0.38) | PTGDR2ALDH1A1 | |
| SCHEMBL21027860 | 0.71 | PTGDR2 (0.49) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21027861 | 0.70 | PTGDR2 (0.43) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21027854 | 0.69 | PTGDR2 (0.46) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028018 | 0.69 | PTGDR2 (0.34) | PTGDR2PTGDRTDP1 | |
| SCHEMBL21027853 | 0.67 | PTGDR2 (0.46) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21027872 | 0.67 | PTGDR2 (0.43) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028284 | 0.65 | HTR2A (0.46) | PTGDR2PTGDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |