Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028026 | 0.85 | PTGDR2 (0.46) | FFAR1PTGDRTBXA2RMEN1KMT2A | |
| SCHEMBL21028289 | 0.80 | PTGDR2 (0.45) | PTGDRTBXA2RPTGDR2 | |
| SCHEMBL21028023 | 0.76 | PTGDR2 (0.39) | PTGDRKDM4EPTGDR2ALDH1A1 | |
| SCHEMBL21028076 | 0.75 | KDM4E (0.42) | FFAR1PTGDRTBXA2RKDM4EMEN1 | |
| SCHEMBL21027975 | 0.72 | PTGDR2 (0.44) | PTGDRTBXA2RHTR6KDM4EMEN1 | |
| SCHEMBL21028002 | 0.71 | PTGDR2 (0.42) | PTGDRTBXA2RMEN1KMT2AHSD17B10 | |
| SCHEMBL21028286 | 0.71 | PTGDR2 (0.39) | PTGDRTBXA2RKMT2APTGDR2 | |
| SCHEMBL21028081 | 0.67 | PTGDR2 (0.39) | PTGDRPTGDR2 | |
| SCHEMBL21028288 | 0.65 | PTGDR2 (0.52) | PTGDRTBXA2RPTGDR2 | |
| SCHEMBL24141336 | 0.64 | PER2 (0.39) | PTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |