Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027858 | 0.86 | PTGDR2 (0.50) | PTGDR2TBXA2RPTGDRFABP4 | |
| SCHEMBL21028287 | 0.85 | PTGDR2 (0.41) | PTGDR2TBXA2RPTGDRRORC | |
| SCHEMBL21028325 | 0.79 | PTGDR2 (0.44) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL21028002 | 0.75 | PTGDR2 (0.42) | PTGDR2TBXA2RPTGDRKMT2A | |
| SCHEMBL21028005 | 0.72 | PTGDR2 (0.38) | PTGDR2TBXA2RPTGDRRORC | |
| SCHEMBL21028080 | 0.71 | FFAR1 (0.39) | PTGDR2TBXA2RPTGDRKMT2A | |
| SCHEMBL21027975 | 0.71 | PTGDR2 (0.44) | PTGDR2TBXA2RPTGDRKMT2A | |
| SCHEMBL21028015 | 0.67 | ALDH1A1 (0.38) | PTGDR2KMT2ACYP1A2 | |
| SCHEMBL21028077 | 0.67 | MEN1 (0.41) | KMT2ACYP1A2 | |
| SCHEMBL21027972 | 0.67 | PTGDR2 (0.45) | PTGDR2PTGDRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |