SCHEMBL21028702

SCHEMBL21028702

CN(C)C=C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL256529 0.67
SCHEMBL24160898 0.67
SCHEMBL17089010 0.67
SCHEMBL165058 0.67
SCHEMBL15066758 0.65
SCHEMBL22924741 0.65
SCHEMBL249854 0.65
SCHEMBL15066759 0.65
SCHEMBL6889735 0.65
SCHEMBL2727302 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11858875-B2 Propenylamines and methods of making and using same 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-02 US disclosed
CN-115215923-A Macrocyclic broad spectrum antibiotics 豪夫迈·罗氏有限公司 2022-10-21 CN disclosed
CN-114007605-B Macrocyclic broad spectrum antibiotics 豪夫迈·罗氏有限公司 2022-07-15 CN disclosed
CN-114007605-A Macrocyclic broad spectrum antibiotics 豪夫迈·罗氏有限公司 2022-02-01 CN disclosed
EP-2240452-B1 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES AS PI3 KINASE MODULATORS, THEIR COMPOSITIONS AND USES INTELLIKINE LLC (US) 2019-05-29 EP disclosed
US-20170283365-A1 NITROGEN CONTAINING HYDROFLUOROETHERS AND METHODS OF USING SAME 3M INNOVATIVE PROPERTIES COMPANY 2017-10-05 US disclosed