Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450951 | 0.84 | TSHR (0.33) | TP53TSHRHSD17B10 | |
| SCHEMBL9987072 | 0.83 | — | — | |
| SCHEMBL17233403 | 0.83 | TSHR (0.46) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL7905900 | 0.82 | ALDH1A1 (0.39) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL21028896 | 0.81 | — | — | |
| SCHEMBL14493845 | 0.77 | ALDH1A1 (0.38) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL13435347 | 0.77 | TSHR (0.40) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL1484429 | 0.77 | TSHR (0.40) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL15453370 | 0.77 | MGAM (0.48) | TP53TSHRHSD17B10MGAMGAA | |
| SCHEMBL8666421 | 0.76 | ALDH1A1 (0.37) | TP53TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2880008-B1 | PROCESS FOR PREPARING SPIRO[2.5]OCTANE-5,7-DIONE | BOEHRINGER INGELHEIM INT (DE) | 2019-05-29 | — | — | EP | disclosed |