Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196856 | 0.75 | IDO1 (0.46) | MEN1KMT2AIDO1LMNAALDH1A1 | |
| SCHEMBL21028422 | 0.73 | IDO1 (0.46) | IDO1CYP2C9CYP2C19ALDH1A1ALOX12 | |
| SCHEMBL19649630 | 0.71 | IDO1 (0.42) | MEN1KMT2AIDO1LMNAALDH1A1 | |
| SCHEMBL5187558 | 0.71 | IDO1 (0.38) | MEN1KMT2AIDO1LMNATAAR1 | |
| SCHEMBL11431913 | 0.71 | HDAC1 (0.49) | MEN1KMT2ALMNAHDAC1HDAC3 | |
| SCHEMBL828091 | 0.71 | ALDH1A1 (0.41) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL828090 | 0.71 | ALDH1A1 (0.41) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL3236997 | 0.71 | ALDH1A1 (0.41) | HDAC1HDAC3HDAC2HDAC6HDAC4 | |
| SCHEMBL9490107 | 0.69 | IDO1 (0.50) | MEN1KMT2AIDO1LMNAALDH1A1 | |
| SCHEMBL11429265 | 0.69 | HDAC4 (0.49) | MEN1KMT2ALMNAHDAC1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126329-B1 | N-HYDROXYMETHANESULFONAMIDE NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS INC (US) | 2019-05-29 | — | — | EP | disclosed |