Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457596 | 0.90 | IDO1 (0.42) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL9357288 | 0.82 | SIGMAR1 (0.46) | IDO1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL196856 | 0.78 | IDO1 (0.46) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL7105383 | 0.78 | IDO1 (0.46) | IDO1LMNACYP2A6TAAR1AGXT | |
| Bromide SCHEMBL7100724 | 0.76 | IDO1 (0.44) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL19649630 | 0.74 | IDO1 (0.42) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL1106684 | 0.71 | IDO1 (0.58) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL2135113 | 0.71 | TAAR1 (0.68) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL2323147 | 0.71 | SIGMAR1 (0.44) | IDO1TAAR1AGXTSLC6A4CHRNA4 | |
| SCHEMBL21028903 | 0.69 | MEN1 (0.39) | IDO1LMNATAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379464-B1 | ARALIPHATIC SULFONIUM SALTS AND THEIR USE | CIBA-GEIGY AG (CH) | 1993-02-10 | — | — | EP | claimed |