SCHEMBL2102949

SCHEMBL2102949

CCCC[Si](CC)(NC)NC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
ALDH1A1 P00352 1/20 0.35
EPHX1 P07099 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL236457 0.88 TSHR (0.38) TSHRALDH1A1EPHX1LMNATHRB
SCHEMBL2101081 0.83 TSHR (0.35) TSHRALDH1A1EPHX1LMNATHRB
SCHEMBL2099756 0.82
SCHEMBL2101198 0.76 TSHR (0.38) TSHRALDH1A1EPHX1LMNA
SCHEMBL235324 0.75
SCHEMBL2272202 0.72 EPHX1 (0.32) TSHREPHX1LMNATHRB
SCHEMBL15309856 0.72 EPHX1 (0.32) TSHREPHX1LMNATHRB
SCHEMBL233647 0.71 TSHR (0.35) TSHRALDH1A1EPHX1LMNATHRB
SCHEMBL2269940 0.71 TSHR (0.35) TSHRALDH1A1EPHX1LMNATHRB
SCHEMBL2269857 0.70 EPHX1 (0.31) TSHREPHX1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed