SCHEMBL2269857

SCHEMBL2269857

CCCC[Si](C)(CC)NC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270480 0.89 TSHR (0.33) EPHX1LMNATSHR
SCHEMBL2267126 0.83
SCHEMBL2276813 0.77 TSHR (0.31) TSHR
SCHEMBL2268719 0.76
SCHEMBL2100900 0.72 TSHR (0.33) EPHX1LMNATSHR
SCHEMBL17830151 0.72
SCHEMBL2269332 0.70 TSHR (0.33) LMNATSHR
SCHEMBL2102949 0.70 TSHR (0.35) EPHX1LMNATSHR
SCHEMBL2272202 0.70 EPHX1 (0.32) EPHX1LMNATSHR
SCHEMBL15309856 0.70 EPHX1 (0.32) EPHX1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed