Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12166264 | 0.98 | KMT2A (0.51) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL21030901 | 0.96 | KMT2A (0.53) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL12166272 | 0.96 | KMT2A (0.49) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL12166284 | 0.94 | KMT2A (0.47) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL18562524 | 0.94 | KMT2A (0.55) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL23615528 | 0.93 | MAPT (0.54) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL12166275 | 0.92 | KMT2A (0.46) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10039374 | 0.91 | KMT2A (0.60) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL12188081 | 0.89 | L3MBTL1 (0.62) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL17051653 | 0.88 | KMT2A (0.53) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-20190161497-A1 | SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | KCNQ2, KCNQ1, KCNQ4 | KMT2A 1221/4885MEN1 3802/4885ALDH1A1 865/4885 |
| US-20190161497-A1 | SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES | KCNQ2, KCNQ1, KCNQ4 | KMT2A 1221/4885MEN1 3802/4885ALDH1A1 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.