Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103586 | 0.82 | PTGDR2 (0.47) | PPARAPPARGPTGDR2KDM4E | |
| SCHEMBL2104209 | 0.79 | TSHR (0.46) | PPARAPPARGTSHRHTR2AHTR2C | |
| SCHEMBL3345930 | 0.77 | TSHR (0.69) | PPARAPPARGTSHRHTR2AHTR2C | |
| SCHEMBL2099802 | 0.77 | TSHR (0.69) | PPARAPPARGTSHRHTR2AHTR2C | |
| SCHEMBL1988977 | 0.72 | PTGDR2 (0.45) | PPARAPPARGPTGDR2 | |
| SCHEMBL31503199 | 0.72 | PPARA (0.71) | PPARAPPARGTSHRHTR2AHTR2C | |
| SCHEMBL2103120 | 0.71 | TSHR (0.47) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| SCHEMBL541271 | 0.70 | PPARA (0.68) | PPARAPPARGTSHRHTR2AHTR2C | |
| SCHEMBL9780844 | 0.70 | PPARA (0.68) | PPARAPPARGTSHRHTR2AHTR2C | |
| SCHEMBL22805341 | 0.69 | PPARA (0.48) | PPARAPPARGTSHRHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163727-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |