Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103123 | 0.82 | PPARA (0.48) | PTGDR2PPARAPPARGKDM4E | |
| SCHEMBL3343296 | 0.80 | PTGDR2 (0.54) | PTGDR2PPARAPPARGABCB11FFAR1 | |
| SCHEMBL2103584 | 0.73 | ABCB11 (0.42) | PTGDR2PPARGABCB11HTTCYP2C19 | |
| SCHEMBL23203532 | 0.71 | PTGDR2 (0.56) | PTGDR2PPARAFFAR1MRGPRX4 | |
| SCHEMBL5280821 | 0.71 | PTGDR2 (0.63) | PTGDR2 | |
| SCHEMBL2103588 | 0.70 | KDM4E (0.40) | PTGDR2PPARAHTTCYP2C19MRGPRX4 | |
| SCHEMBL11440769 | 0.69 | FFAR1 (0.56) | PTGDR2PPARAPPARGFFAR1MRGPRX4 | |
| SCHEMBL531737 | 0.67 | L3MBTL1 (0.47) | PTGDR2HTTCYP2C19KDM4ECYP1A2 | |
| SCHEMBL30760989 | 0.67 | L3MBTL1 (0.47) | PTGDR2HTTCYP2C19KDM4ECYP1A2 | |
| SCHEMBL28037427 | 0.67 | PDE2A (0.36) | HTTCYP2C19MRGPRX4KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163727-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |