SCHEMBL21031685

SCHEMBL21031685

CCCCCCCCC1(CCCCCCCC)c2ccccc2-c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(-c5ccc6c(c5)C(C)(C)c5cc(B7OC(C)(C)C(C)(C)O7)ccc5-6)ccc3-4)cc21

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.42
LPL P06858 13/20 0.42
DGAT1 O75907 1/20 0.32
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22990007 1.00 LIPG (0.42) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL20205740 1.00 LIPG (0.42) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL13103886 1.00 LIPG (0.42) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL13103907 1.00 LIPG (0.42) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL13103915 1.00 LIPG (0.42) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL24257892 0.97 LIPG (0.40) LIPGLPLDGAT1PRMT5WDR77
SCHEMBL22389178 0.96 LIPG (0.44) LIPGLPLDGAT1PDK2
SCHEMBL24257889 0.96 LIPG (0.44) LIPGLPLDGAT1PDK2
SCHEMBL26050388 0.96 LIPG (0.44) LIPGLPLDGAT1PDK2
SCHEMBL22990010 0.96 LIPG (0.44) LIPGLPLDGAT1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11578063-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 US disclosed
US-11365167-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-06-21 US disclosed
EP-3792235-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2021-03-17 EP disclosed
US-20210053894-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-25 US disclosed
US-20210005821-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-01-07 US disclosed
US-20200369678-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-11-26 US disclosed
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-03 US disclosed
US-20200144505-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2020-05-07 US disclosed
WO-2019170572-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed
WO-2019101833-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885
US-20210053894-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885
US-11578063-B2 Materials for organic electroluminescent devices GPX1, EPCAM, EFNA1 LIPG 2692/4885LPL 3880/4885DGAT1 1504/4885
US-20210005821-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885
US-11365167-B2 Materials for organic electroluminescent devices L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885
US-20200369678-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885DGAT1 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.