Sugi Predict

Sugi Predict / Compounds / SCHEMBL21032070

SCHEMBL21032070

SCHEMBL21032070

c1ccc(-c2ccc3ccc4ccc(-c5c6ccccc6nc6sc7ccccc7c56)nc4c3n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP1 P09874 1/20 0.35
▸ LIMK1 P53667 2/20 0.34
▸ RAB9A P51151 4/20 0.33
▸ NPC1 O15118 3/20 0.33
▸ ELANE P08246 1/20 0.33
▸ ACHE P22303 1/20 0.33
▸ ESR1 P03372 3/20 0.33
▸ ESR2 Q92731 3/20 0.33
▸ LMNA P02545 3/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21031294 0.94 KDM4E (0.37) PARP1LIMK1RAB9ANPC1ELANE
SCHEMBL21031300 0.90 PARP1 (0.34) PARP1LIMK1RAB9ANPC1ELANE
SCHEMBL21031299 0.86 LMNA (0.38) RAB9ANPC1ELANEESR1LMNA
SCHEMBL21032058 0.85 TOP1 (0.37) RAB9ANPC1ELANEESR1LMNA
SCHEMBL21031295 0.82 TOP1 (0.38) PARP1RAB9ANPC1ESR1ESR2
SCHEMBL25847632 0.81 TNKS (0.36) PARP1LIMK1RAB9ANPC1ACHE
SCHEMBL21031438 0.81 MEN1 (0.41) ACHEESR1ESR2LMNAKDM4E
SCHEMBL21031441 0.80 ACHE (0.42) ACHEESR1ESR2LMNAKDM4E
SCHEMBL21031442 0.79 MEN1 (0.42) ACHEESR1ESR2LMNAKDM4E
SCHEMBL25847669 0.78 ESR1 (0.44) ELANEESR1ESR2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 — — US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 — — US disclosed
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-05-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 PARP1 1863/4885LIMK1 1827/4885RAB9A 2910/4885
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES KCNQ2, KCNQ1, KCNQ4 PARP1 1863/4885LIMK1 1827/4885RAB9A 2910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.