Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032217 | 0.74 | PTGDR2 (0.66) | PTGDR2 | |
| SCHEMBL21032466 | 0.72 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL21032709 | 0.72 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL21032164 | 0.71 | PTGDR2 (0.65) | PTGDR2ALDH1A1 | |
| SCHEMBL21031858 | 0.70 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL21266666 | 0.69 | PTGDR2 (1.00) | PTGDR2PLA2G2A | |
| SCHEMBL14979223 | 0.69 | TDP1 (0.53) | PTGDR2PLA2G2AALDH1A1TDP1MEN1 | |
| SCHEMBL21032568 | 0.69 | PTGDR2 (0.38) | PTGDR2MEN1KMT2A | |
| SCHEMBL21031848 | 0.67 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL21031903 | 0.67 | PTGDR2 (0.57) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-B1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |