SCHEMBL2103298

SCHEMBL2103298

[SiH3]C(Cl)=C(Cl)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
DAO P14920 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
ALDH1A1 P00352 4/20 0.45
HIF1A Q16665 2/20 0.45
CES1 P23141 5/20 0.39
CES2 O00748 4/20 0.39
SRD5A2 P31213 1/20 0.39
ESR1 P03372 1/20 0.37
MAPK1 P28482 2/20 0.37
TRPA1 O75762 1/20 0.37
GSK3B P49841 1/20 0.37
F2 P00734 2/20 0.36
CYP3A4 P08684 2/20 0.36
MAPT P10636 2/20 0.36
BLM P54132 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
F10 P00742 1/20 0.36
F12 P00748 1/20 0.36
F7 P08709 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3940728 0.82 TSHR (0.56) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL3940726 0.82 TSHR (0.56) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL2270832 0.81 TSHR (0.43) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL2270825 0.78 CES2 (0.39) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL28858448 0.78 TSHR (0.46) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL7875628 0.77 TSHR (0.50) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL59763 0.77 TSHR (0.50) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL18294893 0.74 ESR1 (0.50) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL1062320 0.72 CES1 (0.39) TSHRDAONAPRTALDH1A1HIF1A
SCHEMBL7644150 0.72 TSHR (0.46) TSHRDAONAPRTALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116675864-A Preparation method of polysilabozane capable of self-crosslinking and adjustable in boron content 宁波杭州湾新材料研究院 2023-09-01 CN claimed
CN-116675864-A Preparation method of polysilabozane capable of self-crosslinking and adjustable in boron content 宁波杭州湾新材料研究院 2023-09-01 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed
US-5851942-A Preparation of boron-doped silicon carbide fibers UNIVERSITY OF FLORIDA (US) 1998-12-22 US disclosed
EP-0636163-B1 CROSSLINKABLE SILARYLENE-SILOXANE COPOLYMERS MINNESOTA MINING & MFG (US) 1998-09-16 EP disclosed
US-5792416-A Preparation of boron-doped silicon carbide fibers UNIVERSITY OF FLORIDA (US) 1998-08-11 US disclosed
US-5578380-A Crosslinkable silarylene-siloxane copolymers MINNESOTA MINING & MFG (US) 1996-11-26 US disclosed
EP-0636163-A1 CROSSLINKABLE SILARYLENE-SILOXANE COPOLYMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-01 EP disclosed
US-5346980-A Crosslinkable silarylene-siloxane copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-09-13 US disclosed
US-5268336-A Preparation of substantially polycrystalline silicon carbide fibers from methylpolydisilylazanes DOW CORNING CORPORATION (US) 1993-12-07 US disclosed
WO-1993021278-A1 CROSSLINKABLE SILARYLENE-SILOXANE COPOLYMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-28 WO disclosed
EP-0161751-B1 PROCESS FOR THE PREPARATION OF POLYMETALLO(DISILY) SILAZANE POLYMERS AND THE POLYMERS THEREFROM DOW CORNING CORPORATION (US) 1989-09-20 EP disclosed
EP-0161751-A1 Process for the preparation of polymetallo(disily) silazane polymers and the polymers therefrom DOW CORNING CORPORATION (US) 1985-11-21 EP disclosed
US-4482689-A CERAMICS DOW CORNING CORPORATION (US) 1984-11-13 US disclosed