Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032931 | 0.89 | LMNA (0.72) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL21033102 | 0.87 | LMNA (0.76) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL21033042 | 0.87 | CA12 (0.62) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL21033118 | 0.84 | LMNA (0.64) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL830882 | 0.83 | CA12 (0.77) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL21032727 | 0.83 | KDM4E (0.67) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL25010874 | 0.82 | LMNA (0.69) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL21033631 | 0.82 | LMNA (0.77) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL21033641 | 0.82 | LMNA (0.68) | LMNAPKMNPSR1MEN1KMT2A | |
| SCHEMBL21033120 | 0.82 | LMNA (1.00) | LMNAPKMNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104201-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS | Zander Therapeutics, Inc. (US) | 2019-05-31 | — | — | WO | disclosed |