Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033102 | 0.92 | LMNA (0.76) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL21033100 | 0.92 | CA12 (0.68) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL20435631 | 0.86 | PKM (0.72) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL21033640 | 0.86 | CA12 (0.65) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL830280 | 0.85 | CA12 (0.77) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL21033627 | 0.84 | LMNA (0.76) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL21033387 | 0.84 | CA12 (0.59) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL21033042 | 0.84 | CA12 (0.62) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL21033644 | 0.84 | LMNA (0.85) | LMNAPKMKMT2AMEN1NPSR1 | |
| SCHEMBL21033639 | 0.83 | RXFP1 (0.81) | LMNAPKMKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104201-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS | Zander Therapeutics, Inc. (US) | 2019-05-31 | — | — | WO | disclosed |