Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033127 | 0.89 | TP53 (0.80) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL21033402 | 0.84 | RXFP1 (0.55) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL21033400 | 0.83 | LMNA (0.69) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL21033403 | 0.81 | ATM (0.55) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL21033121 | 0.81 | RXFP1 (0.81) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL20435649 | 0.79 | MAPT (0.76) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL21032944 | 0.79 | TP53 (0.79) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL21032942 | 0.78 | RXFP1 (1.00) | RXFP1TP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL11297367 | 0.77 | MAOB (0.79) | RXFP1MAPTMEN1KMT2AMAOB | |
| SCHEMBL21032749 | 0.77 | RXFP1 (0.69) | RXFP1TP53MAPTTHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104201-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS | Zander Therapeutics, Inc. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |