Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605019 | 1.00 | TSHR (0.43) | TSHRALDH1A1TET2AKR1B1CA2 | |
| SCHEMBL381209 | 1.00 | TSHR (0.43) | TSHRALDH1A1TET2AKR1B1CA2 | |
| SCHEMBL33108 | 0.92 | FDPS (0.46) | TSHRALDH1A1AKR1B1PPARGPPARD | |
| SCHEMBL7081692 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL438946 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL6556927 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL35099 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL9097992 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL3916862 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL126859 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639095-B1 | Enantioselective synthesis employing 10-camphorsulfonamide as chiral auxiliary through 1,3-dioxolanones | Chan, Hardy W. | 2003-10-28 | — | — | US | claimed |
| EP-1233939-A4 | PROCESS FOR PREPARING OPTICALLY ACTIVE ALPHA-HYDROXY ACIDS AND DERIVATIVES THEREOF | SCINOPHARM SINGAPORE PTE LTD (SG) | 2003-07-09 | — | — | EP | claimed |
| CN-1379748-A | Process for preparing optically active alpha-hydroxy acids and derivatives thereof | SCINOPHARM SINGAPORE PTE LTD (SG) | 2002-11-13 | — | — | CN | claimed |
| EP-1233939-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE ALPHA-HYDROXY ACIDS AND DERIVATIVES THEREOF | Scinopharm Singapore Pte Ltd. (SG) | 2002-08-28 | — | — | EP | claimed |
| WO-2001040153-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE α-HYDROXY ACIDS AND DERIVATIVES THEREOF | SCINOPHARM SINGAPORE PTE LTD. (SG) | 2001-06-07 | — | — | WO | claimed |
| US-8163727-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |
| US-6639095-B1 | Enantioselective synthesis employing 10-camphorsulfonamide as chiral auxiliary through 1,3-dioxolanones | Chan, Hardy W. | 2003-10-28 | — | — | US | disclosed |
| CN-1379748-A | Process for preparing optically active alpha-hydroxy acids and derivatives thereof | SCINOPHARM SINGAPORE PTE LTD (SG) | 2002-11-13 | — | — | CN | disclosed |
| US-4633025-A | INTERMEDIATES FOR SYNTHESIS OF PG ANALOGS | MILES LABORATORIES, INC. (US) | 1986-12-30 | — | — | US | disclosed |
| US-4060691-A | 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl}heptanoic acids and esters | G. D. SEARLE & CO. (US) | 1977-11-29 | — | — | US | disclosed |