Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381209 | 1.00 | TSHR (0.43) | TSHRALDH1A1TET2AKR1B1CA2 | |
| SCHEMBL2103333 | 1.00 | TSHR (0.43) | TSHRALDH1A1TET2AKR1B1CA2 | |
| SCHEMBL33108 | 0.92 | FDPS (0.46) | TSHRALDH1A1AKR1B1PPARGPPARD | |
| SCHEMBL7081692 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL438946 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL6556927 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL35099 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL9097992 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL3916862 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL126859 | 0.90 | FDPS (0.48) | TSHRALDH1A1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |
| EP-1072653-B1 | Aqueous ink and its use | FRANCOTYP POSTALIA AG (DE) | 2005-03-02 | — | — | EP | claimed |
| EP-1072653-A2 | Aqueous ink and its use | Francotyp-Postalia Aktiengesellschaft & Co. (DE) | 2001-01-31 | — | — | EP | claimed |
| EP-0198348-B1 | PROCESS FOR PREPARING (+)S-2-HYDROXY-2-METHYL-HEXANOIC ACID | MILES INC. (US) | 1990-01-03 | — | — | EP | claimed |
| US-4668822-A | Method for preparing (+)S-2--hydroxy-2-methyl-hexanoic acid | MILES LABORATORIES, INC. (US) | 1987-05-26 | — | — | US | claimed |
| EP-0198348-A2 | Process for preparing (+)S-2-hydroxy-2-methyl-hexanoic acid | MILES INC. (US) | 1986-10-22 | — | — | EP | claimed |
| US-20150240272-A1 | LACTATE PRODUCTION PROCESS | PLAXICA LIMITED (GB) | 2015-08-27 | — | — | US | disclosed |
| WO-2014045036-A1 | LACTATE PRODUCTION PROCESS | PLAXICA LIMITED (GB) | 2014-03-27 | — | — | WO | disclosed |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | disclosed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | disclosed |
| US-4668822-A | Method for preparing (+)S-2--hydroxy-2-methyl-hexanoic acid | MILES LABORATORIES, INC. (US) | 1987-05-26 | — | — | US | disclosed |
| US-4668822-A | Method for preparing (+)S-2--hydroxy-2-methyl-hexanoic acid | MILES LABORATORIES, INC. (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0198348-A2 | Process for preparing (+)S-2-hydroxy-2-methyl-hexanoic acid | MILES INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| EP-0198348-A2 | Process for preparing (+)S-2-hydroxy-2-methyl-hexanoic acid | MILES INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| EP-0198348-A2 | Process for preparing (+)S-2-hydroxy-2-methyl-hexanoic acid | MILES INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| US-4060691-A | 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl}heptanoic acids and esters | G. D. SEARLE & CO. (US) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | ACKR3, KIT, C3AR1 | TSHR 3712/4885ALDH1A1 1235/4885TET2 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.