Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 10/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11914803 | 0.78 | ALDH1A3 (0.60) | ALDH1A3SLC2A1ALDH1A1NPC1RAB9A | |
| SCHEMBL871995 | 0.77 | NPC1 (0.50) | ALDH1A1NPC1RAB9APAX8SMN1; SMN2 | |
| SCHEMBL13770942 | 0.76 | ALDH1A3 (0.42) | ALDH1A3SLC2A1ALDH1A1NPC1RAB9A | |
| SCHEMBL21033298 | 0.75 | EGLN1 (0.51) | ALDH1A3SLC2A1ALDH1A1ALDH1A2EGLN1 | |
| SCHEMBL11914399 | 0.75 | ALDH1A3 (0.44) | ALDH1A3SLC2A1ALDH1A1NPC1RAB9A | |
| SCHEMBL30845768 | 0.74 | TGFBR1 (0.54) | ALDH1A3EGLN1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL31035779 | 0.73 | ROCK1 (0.32) | — | |
| SCHEMBL21033565 | 0.71 | KDM4E (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11914416 | 0.71 | ALDH1A3 (0.58) | ALDH1A3ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL869867 | 0.69 | APP (0.43) | ALDH1A3ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019102494-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-05-31 | — | — | WO | disclosed |