SCHEMBL21034846

SCHEMBL21034846

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nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
PTPN1 P18031 2/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TYR P14679 5/20 0.36
MAPT P10636 1/20 0.36
POLB P06746 1/20 0.36
AMY2A P04746 2/20 0.36
SYNJ2 O15056 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21035195 0.83 PTPN1 (0.45) L3MBTL1PTPN1MEN1KMT2ATYR
Griffonin SCHEMBL21034801 0.79 MAPT (0.43) L3MBTL1PTPN1MEN1KMT2ATYR
Griffonin SCHEMBL20995242 0.79 MAPT (0.43) L3MBTL1PTPN1MEN1KMT2ATYR
Griffonin SCHEMBL28797041 0.79 MAPT (0.43) L3MBTL1PTPN1MEN1KMT2ATYR
Griffonin SCHEMBL21034847 0.79 MAPT (0.43) L3MBTL1PTPN1MEN1KMT2ATYR
SCHEMBL21035198 0.71 PTPN1 (0.35) L3MBTL1PTPN1MEN1KMT2AMAPT
Trehalose SCHEMBL23029503 0.66 MEN1 (0.57) L3MBTL1PTPN1MEN1KMT2ATYR
Trehalose SCHEMBL17072366 0.66 MEN1 (0.57) L3MBTL1PTPN1MEN1KMT2ATYR
Trehalose SCHEMBL13465987 0.66 MEN1 (0.57) L3MBTL1PTPN1MEN1KMT2ATYR
Trehalose SCHEMBL25304700 0.66 MEN1 (0.57) L3MBTL1PTPN1MEN1KMT2ATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11179408-B2 Use of cyanoglucosides and pharmaceutical formulations thereof in the treatment of diabetes UNIVERSITÉ DE GENÈVE (CH) 2021-11-23 US disclosed
US-20190160085-A1 USE OF CYANOGLUCOSIDES AND PHARMACEUTICAL FORMULATIONS THEREOF IN THE TREATMENT OF DIABETES UNIVERSIDADE ESTADUAL PAULISTA JULIO DE MESQUITA FILHO (BR) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190160085-A1 USE OF CYANOGLUCOSIDES AND PHARMACEUTICAL FORMULATIONS THEREOF IN THE TREATMENT OF DIABETES SLC5A1, SLC5A2, GYS2 L3MBTL1 1912/4885PTPN1 3362/4885MEN1 1286/4885
US-11179408-B2 Use of cyanoglucosides and pharmaceutical formulations thereof in the treatment of diabetes SLC5A2, SLC5A1, GYS2 L3MBTL1 1839/4885PTPN1 3241/4885MEN1 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.