Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035576 | 1.00 | ACACB (0.41) | ACACBMMP9MMP2MCL1ADAM17 | |
| SCHEMBL21035514 | 0.94 | ACACB (0.42) | ACACBMMP9ADAM17MMP1MMP13 | |
| SCHEMBL21035679 | 0.94 | ACACB (0.42) | ACACBMMP9ADAM17MMP1MMP13 | |
| SCHEMBL21035408 | 0.92 | ACACB (0.41) | ACACBMMP9MCL1ADAM17MMP1 | |
| SCHEMBL21035643 | 0.92 | ACACB (0.41) | ACACBMMP9MCL1ADAM17MMP1 | |
| SCHEMBL21035143 | 0.92 | ACACB (0.41) | ACACBMMP9MCL1ADAM17MMP1 | |
| SCHEMBL21034927 | 0.90 | ACACB (0.42) | ACACBMMP9MMP2ADAM17MMP1 | |
| SCHEMBL21034946 | 0.86 | MMP1 (0.38) | MMP9MMP2MCL1ADAM17MMP1 | |
| SCHEMBL21035572 | 0.86 | MMP1 (0.38) | MMP9MMP2MCL1ADAM17MMP1 | |
| SCHEMBL21035404 | 0.86 | MMP9 (0.36) | MMP9MMP2MCL1ADAM17MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |