Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20325460 | 0.82 | PARP10 (0.55) | PARP10PARP15GRM2PARP2MAOA | |
| SCHEMBL20325660 | 0.80 | PARP15 (0.54) | PARP10PARP15GRM2PARP2HPGD | |
| SCHEMBL28067029 | 0.74 | PARP10 (0.53) | PARP10PARP15PARP2MAOAMAOB | |
| SCHEMBL20038304 | 0.74 | PARP10 (0.49) | PARP10PARP15GRM2PARP2MAOA | |
| SCHEMBL31038329 | 0.74 | GPR119 (0.46) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL25243983 | 0.74 | GPR119 (0.46) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL1564278 | 0.74 | CHRNB2 (0.58) | PARP10PARP15GRM2MAOAMAOB | |
| SCHEMBL18706934 | 0.74 | CHRNB2 (0.57) | PARP10PARP15PARP2MAOAMAOB | |
| SCHEMBL16085032 | 0.73 | NQO1 (0.45) | PARP10 | |
| SCHEMBL18088475 | 0.73 | PARP15 (0.51) | PARP10PARP15PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |